Calvin Denham is married to Harriet Thompson. They were married on February 2, 1964 at the Drakes Creek Baptist Church. They have one son Todd Denham (Roni Ann) of Winchester, Ky. One granddaughter, Makenna Rose Denham. He and his wife are members of the Stanford Baptist Church where he serves as a Deacon.

Calvin retired from First Southern National Bank in 2020 after being in the banking industry for 52 years.

Calvin serves on the Lincoln County Board of Adjustments, First Priority Board, Lincoln County Baptist Budget Committee and The Gideon's International as a speaker, Habitat for Humanity. Calvin has been with Spurlin Funeral Home since 2010 where he serves greeting families at visitation and funerals.